Navigating the Fourth-Line Breakthroughs in GIST Therapeutics

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2025-12-26 09:11:19 -

What defines the current shift in advanced GIST management? Gastrointestinal Stromal Tumors (GIST) have historically presented a challenge once patients progress past initial tyrosine kinase inhibitor (TKI) therapies. Until recently, the therapeutic ceiling was reached relatively quickly. However, the introduction of switch-control inhibitors has redefined the late-stage treatment algorithm....

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